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In this wacky year, the Big Ten conference will have 12 teams and the Big 12 will have only ten after the departure of Colorado and Nebraska. The Big 12 landscape will change significantly without those two. Here is an early look at the college football betting odds for who in the Big 12 has the best chance to win the 2012 national championship.

The Oklahoma Sooners top the list as the most likely team in the nation to go all the way this year with 2012 BCS championship odds of +370. The dynamic passing duo of quarterback Landry Jones and Ryan Broyles will be back, along with linebacker Travis Lewis and four starters on the offensive line.

Like some kind of dream season, the Baylor Bears are a ranked team. After finishing at the bottom of their conference almost every year, the Bears are 6-2 and ranked 25th. They beat a quality Kansas State team 47-42 and will look for another big win against the Texas Longhorns. Texas has been uncharacteristically weak this year, going just 4-3, and losing their most recent game to lowly Iowa State. They do have the home field advantage though, and are a seven point favorite according to the college football odds.

Top 25 teams from the Big 12 collide this Saturday as the 8th ranked Oklahoma Sooners take on the 21st ranked Texas Longhorns. While these two teams don’t look as powerful as they have been in the past, there are sure to be plenty of fireworks in the 105th meeting between these programs.

Texas will try to rebound after a shocking loss to UCLA, 34-12.The Sooners defeated Cincinnati 31-29, their third victory by seven points or less this season. The college football odds have Oklahoma as a 3.5 favorite.

2009 Total Offense Rank (yards per game): 29
2009 Total Defense Rank (yards per game): 3

Just a few months after losing the National Championship game to Alabama, the Texas Longhorns are back with a ton of talent and are ready to make another run. Some key pieces from last year’s squad are gone, but based on head coach Mack Brown’s historical success and terrific recruiting, Texas is a national championship contender once again.